Molecular clock of viral evolution, and the neutral theory.

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The neutral theory of molecular evolution.

By the early 1960s amino acid sequences of hemoglobins and cytochrome c for many mammals had been determined. When the sequences were compared, investigators began to notice that the number of amino acid differences between different pairs of mammals seemed to be roughly proportional to the time since they had diverged from one another, as inferred from the fossil record. Zuckerkandl and Paulin...

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By the early 1960s amino acid sequences of hemoglobins and cytochrome c for many mammals had been determined. When the sequences were compared, investigators began to notice that the number of amino acid differences between different pairs of mammals seemed to be roughly proportional to the time since they had diverged from one another, as inferred from the fossil record. Zuckerkandl and Paulin...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1990

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.87.24.10015